What is a typical pathology finding across all forms of AHS?

What is a typical pathology finding across all forms of AHS?

• A. Renal necrosis with hepatic hemorrhage
• B. Pulmonary edema with pleural effusion (peracute); hydropericardium with petechial and ecchymotic hemorrhages of epi/endocardium; edema of mucosa and head/neck tissues
• C. Neural gliosis and brain edema
• D. Splenic rupture and peritonitis

Answer: (B)

Across all forms of African horse sickness, vascular injury from the virus leads to widespread edema and hemorrhages, especially in the lungs, heart, and head/neck tissues. A typical pattern to look for is pulmonary edema with pleural effusion, combined with hydropericardium and small petechial or ecchymotic hemorrhages on the epicardium and endocardium, along with edema of mucous membranes and head/neck tissues. These features reflect the severe capillary leakage that characterizes the disease, and they are seen regardless of the form (peracute, acute, or subacute). This is why the described combination—pulmonary edema with pleural effusion, hydropericardium with heart surface hemorrhages, and mucosal/head-neck edema—best fits African horse sickness across forms. Other options do not align with the typical vascular-leak/edema pattern seen in this disease.

Across all forms of African horse sickness, vascular injury from the virus leads to widespread edema and hemorrhages, especially in the lungs, heart, and head/neck tissues. A typical pattern to look for is pulmonary edema with pleural effusion, combined with hydropericardium and small petechial or ecchymotic hemorrhages on the epicardium and endocardium, along with edema of mucous membranes and head/neck tissues. These features reflect the severe capillary leakage that characterizes the disease, and they are seen regardless of the form (peracute, acute, or subacute).

This is why the described combination—pulmonary edema with pleural effusion, hydropericardium with heart surface hemorrhages, and mucosal/head-neck edema—best fits African horse sickness across forms. Other options do not align with the typical vascular-leak/edema pattern seen in this disease.